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The Science of the Black and Brown Gene

Mendel's Law Simplified: For centuries scientists, physicians and philosophers had been trying to understand the secrets of heredity. From 1856 to 1865, Johann Gregor Mendel bred and raised pea plants, having had some training in statistics. He knew he had to study large numbers of plants, so he identified traits in thousands of plants.

Mendel called the original parents P1 for parent generation and the offspring of the cross F1 for the first filial generation. He called the next cross F2 for second filial generation. When Mendel crossed tall pea plants with the short pea plants of the P1 generation, all of the F1 plants were tall. The same thing happened with each of the seven traits, only one form of each characteristic appeared in the F1 plants. To find out where the characteristic for short plants had went, he crossed the F1 plant to the F1 plant to get F2 plants, in which appeared the short plants again. Not only did it reappear but with a certain predictable mathematical relationship, 1 short and 3 tall. The same relationship, also, showed up for all of the seven traits. The patterns he found in his experiments formed the basis of our present knowledge of genetics.

1. Mendel's first hypothesis was that inherited characteristics are controlled by factors that occur in pairs.
2. Mendel's second hypothesis stated that one factor (dominant) in a pair mask the other (recessive) preventing it from showing its affect.
3. The third hypothesis is that each offspring receives only 1 factor from each parent.
4. The fourth hypothesis is that different factors are inherited separately (such as seed color does not have any connection with the height of a pea plant).

Additonal studies proved the following of dominate color:
1. The color does not skip a generation.
2. On the average a relatively large number of the progeny are affected.
3. Only affected individuals carry the color.
4. With color of this sort, there is less danger of continuing undesirable color in a strain, than is the case with recessive color.
5. The breeding formula for each individual is quite certain.

and the following of recessive color:
1. The color may skip one or more generations.
2. On the average a relatively small percentage of the individuals in the strain carry the color.
3. Only those which carry a pair of genes for that color (exhibit it).
4. Those carrying only one gene can be seen only by mating, hence there is much more danger of accidentally contaminating the strain than is the case with dominant color.
5. The color must come from both sides of the family.

Homozygous is an animal carrying the same form of a gene such as B B. Hetrozygousity is an animal that carries two different forms of the same gene such as B b.

In 1865 Mendel, science teacher and abbot in the monastery of St. Augustine at Bruenn, published a paper on Experiments of Plant Hybridization. He described his experiments in the garden of the monastery and the laws of genetics that he concluded from this. Mendel's Law covers the basic understanding of inheritance.

The value of studying genetics is in understanding how we can predict the likelihood of inheriting particular traits. This can help plant and animal breeders in developing varieties that have more desirable qualities. It can also help people explain and predict patterns of inheritance in family lines.

Now I get to why I've included Mendel's Law. The Bb pair - all cockers have one or the other of this pair of genes which means that all of these dogs are basically black or brown (chocolate). All other colors are color modifiers.

The easiest way to tell if your cocker’s primary color is actually black or brown, regardless of coat color, is to check the color of the nose and toenails. If black, the primary color of the cocker is black. If brown, the primary color is brown. Disregard toenails that are white.

B - produces solid black and is dominant.

b - restricts (dilution) the black color and produces brown (chocolate/liver) and is recessive.

One of the easiest ways to calculate the mathematical probability of inheriting a specific trait was invented by an early 20th century English geneticist named Reginald Punnett. His technique employs what we now call a Punnett square. This is a simple graphical way of discovering all of the potential combinations of genotypes that can occur in children, given the genotypes of their parents. It also shows us the odds of each of the offspring genotypes occurring.

Setting up and using a Punnett square is quite simple once you understand how it works. You begin by drawing a grid of perpendicular lines. Next, you put the genotype of one parent across the top and that of the other parent down the left side. Now, for example, I am going to use the Punnett square to determine the percentage of puppies that I could expect to brown factored in any given mating between Liz E. and Dudley

Note that only one letter goes in each box for the parents. It does not matter which parent is on the side or the top of the Punnett square. Next, all you have to do is fill in the boxes by copying the row and column-head letters across or down into the empty squares. This gives us the predicted frequency of all of the potential genotypes among the offspring each time reproduction occurs.

Therefore, by using the Punnett square I am able to predict with a certain degree of probability that 100% of the puppies that will come from a breeding between Lizzy and Dudley will be brown factored. It is all pretty simple once you understand it . . .


Parent
Parent
Parent
Parent
Brown
Black
Brown
Black

b b

B b

b b

B b

Lizzy
Dudley
Brown
Brown

b b

b b

Progeny
Progeny
Brown
Brown

b b

b b

Progeny
Progeny
Brown
Brown

b b

b b